Automated Push Syringe System for Behavioral Training in Mice

Description:

This video showcases the design and animation of a custom push syringe system developed for training mice in goal-directed actions. The system is engineered with precision to facilitate behavioral experiments and includes the following components:

  • Push Syringe with Screw Mechanism: The syringe piston operates via a screw-in/screw-out mechanism, ensuring precise control of fluid delivery.
  • Servo Motor with Guide Rails: The piston is powered by a servo motor that slides along two lateral guide rails, providing stability and accuracy during operation.
  • Arduino-Controlled Automation: The system is programmed using an Arduino microcontroller, enabling automated control of the servo motor and fluid delivery.

Behavioral Training:

In the described behavioral task, mice are trained to perform a goal-directed action:

  • Task: When an LED light turns on, the mouse must run on a treadmill to receive a reward—one drop of sweet water delivered by the push syringe.
  • Outcome:
    • Correct action (running when the LED is on): Rewarded with a drop of sweet water.
    • Incorrect action (not running or running when the LED is off): Results in white noise and a timeout.

This system allows for precise timing and reward delivery, creating a highly controlled environment for studying behavior and motor learning in mice.

Description